Beverly  McKinney, Biology Teacher
Introduction
Standards 
Objectives
Activities
Assessment 
Results
Resources
Emerging

Technology:

DNA
 

DNA Identification

DNA coil

 
 
 

.
Introduction
Everett Alvarez High School offers Biology 1-2  as a class open to all students who have had or are concurrently taking algebra.  Most students taking this course are sophomores, however many freshmen also qualify for this class.  This class is a survey course in which the first semester covers cellular biology with a significant emphasis on genetics & DNA.
Subject:            Biology 1-2
Topic:               DNA - Structure & Replication
Grade Level:    9-10
Student Pages:  ctap295.ctaponline.org/~bmckinney/student/
Standards Addressed                       Top
                            http://www.cde.ca.gov/board/pdf/science.pdf
        Biology Standard #5:   The genetic composition of cells can be altered by incorporation of 
                                                exogenous DNA into the cells. As a basis for understanding
                                                this concept, students know: 

                    a. the general structures and functions of DNA, RNA, and protein. 

                    b. how to apply base-pairing rules to explain precise copying of DNA during
                        semi-conservative replication, and transcription of information from DNA into
                        mRNA. 

Instructional Objectives
     Students will be able to:
          -Sketch and label the basic structure of the DNA molecule.
          -Make a model of the DNA molecule either on the computer or with available
           materials.
          -Define DNA, DNA replication, helix, base pair, nucleic acid, bond
          -Sketch (or show with a model) the process of replication.
          -Give at least 5 reasons why it is important to know about DNA
i


Student Activities

Introductory Activity

     -Text pre-read:  students skim text chapter on DNA & do quick write on what they believe
      chapter is about. 
     -Pre-test
     -KWL (see form below) : Students write what they think they already know about this topic, & questions 
      they have wondered about that relate to this topic.
     -Brief  lecture on DNA  structureweb site with DNA explanation & sketches of process
 

Enabling Activity(ies)
 PART A.
     -Brief  lecture on DNA importance & structure

     -Student teams to access http://gslc.genetics.utah.edu/basic/dogma/nf1dna.html . Read and follow program
          to make an on-screen DNA molecule by joining base pairs. When done, students will answer the 4 
          questions below the pair joining.

     -Read and take notes on text material on DNA structure.

     -Q&A session

                     *Assessment: Sketch and label a DNA molecule

PART B.
     -Brief lecture on replication

     -Read and take notes on DNA replication from text.

     -Student teams to access http://vector.cshl.org/dnaftb/15/concept/ .Complete parts # 15-20 . At the end
          of each part, complete the "Problem" section.

     -Q&A session

                         *Assessment: Sketch and label a DNA molecule replication
 
 
 
 
 

Culminating Activity

     -Use Microsoft works to prepare a one page report on DNA structure and replication.  Include
          at least one of the images from the website below as a part of your explaination.
                        http://www.ornl.gov/hgmis/publicat/primer/prim1.html#1
 
                                     *Assessment: Building of DNA molecule that can be used to show replication .
 

 
  



Assessment
      Assessment of sketches and models will be on a 5-1 basis with 5 being excellent, 4 being above average, 3 being average, 2 being below average, and 1 being unacceptable.

Rubric:
A. DNA sketch
     5= Nucleic acids named, base pairs properly linked, deoxyribose and phosphate in
             place and labeled, single and double bonds shown, base pairs represented by 
             complimentary shapes & color coded, molecule shown as double helix & twisting.
     4= Nucleic acids named, base pairs properly linked, deoxyribose and phosphate in
             place and labeled, bonding generally shown,base paires represented by complementary 
             shapes molecule shown as double helix & twisting.
     3=Nucleic acids named, base pairs properly linked, deoxyribose and phosphate in place
             and labeled, molecule shown as double helix.
     2=At least 3 of 4 nucleic acids named, base pairs properly linked, deoxyribose & phosphate
             shown in some way.
     1= Less than #2 above.

B. DNA model
      Same as above except in 3D format or on computer in 3D or manipulative format.
 
 

C .DNA replication sketch
     5= Both sides of twisted helix shown, unzipping shown, direction of replication shown, enzyme 
          interaction shown and labeled, correct nucleic acid joining shown and labeled, new
          strand distinguished from parent strand.
     4= Both sides of helix shown, unzipping shown, correct nucleic acid joining shown and labeled.
     3= At least one side of helix shown, correct nucleic acid joining shown and labeled.
     2= At last one side of helix shown, 3 out of 4 nucleic acid joinings shown and labled.
     1= Less that #2 above.

D. Complete KWL final section

E. Complete multiple choice post- test
 

Results
To be posted
 


Web Resources & Supplementary Materials

Introductory Activity
KWL form (make button )

Enabling Activity
DNA introduction
http://gslc.genetics.utah.edu/basic/dogma/nf1dna.html

More DNA information with animation & scientists
http://vector.cshl.org/dnaftb/15/concept/
 

Culminating Activity

Images of DNA
http://www.ornl.gov/hgmis/publicat/primer/prim1.html#1

 

 

School Name:       Everett Alvarez High School
School Location:   1900 Independence Blvd., Salinas, CA 93906
Principal:              Murry Scheckman, mscheckman@salinas.k12.ca.us
Contact:                Beverly McKinney,bmckinney@salinas.k12.ca.us
Last Revised:         27 June 2000